seurat_clusters

c6

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Cardiac muscle contraction	0	0.0011	0.6105	0.7984	1.4846	83	TPM4,COX4I1,COX5A,COX8A,UQCRB,UQCRFS1,COX6C,UQCRH,COX7C,UQCRQ,COX7A2,COX5B,UQCR11,COX7A2L,UQCR10,COX7B,COX6B1,COX6A1,UQCRC2,ATP1B3,CYC1,UQCRC1,UQCRHL,CACNA2D4
Maturity onset diabetes of the young	0	0.0011	0.5933	-0.9648	-2.1352	26	HHEX
Proteasome	0.0001	0.0077	0.5384	0.8256	1.4832	46	PSMB9,PSME2,PSME1,PSMB8,PSMB4,POMP,PSMA1,PSMA4,PSMB10,SEM1,PSMA5,PSME4,PSMD8,PSMB3,PSMA2,PSMB2,PSMD7,PSMC1,PSMB7,PSMA6,PSMA7,PSMB6,PSMF1,ADRM1,PSMA3,PSMD6,PSMD9,PSMD4,PSMD11,PSMC2,PSMC6,PSMB1
Primary immunodeficiency	0.0002	0.0112	0.5188	0.8351	1.4665	37	TAP1,CD8B,JAK3,IL7R,CD8A,CD3D,ADA,CD3E,LCK,ICOS,IL2RG,ORAI1,ZAP70,CD79A,RFX5,RFXANK,CIITA,TNFRSF13C
GABAergic synapse	0.0027	0.1018	0.4317	0.7151	1.3342	89	GABARAPL1,PRKCB,GABARAP,GABARAPL2,GNB1,SLC38A1,GNG5,GNB2,GNG10,GNAI2,ADCY3,PRKCA,ADCY7,ABAT,GNGT2,GNG2,GLUL,GLS,GNB4,NSF,TRAK2,ADCY4,GNG4,CACNA1A,GABRR2,CACNA1C,ADCY9,CACNA1F,GNG7
Morphine addiction	0.0032	0.1018	0.4317	0.7075	1.3217	91	PDE3B,PDE4D,ARRB2,PRKCB,PDE4B,GNB1,PDE7B,GRK2,GNG5,GNB2,GNG10,GNAI2,ADCY3,PDE7A,PRKCA,ADCY7,GNGT2,GNG2,PDE4A,GNAS,GNB4,ADCY4,GRK3,GNG4,CACNA1A,GABRR2,ADCY9,GNG7
Nicotine addiction	0.0073	0.183	0.407	0.7692	1.3594	40	CACNA1A,GABRR2,GABRD,GRIN3B,CHRNB2
Fc gamma R-mediated phagocytosis	0.0084	0.183	0.3807	0.6886	1.2888	96	FCGR3A,RAC2,BIN1,PRKCB,ARPC2,ARPC3,ARPC1B,LAT,ARPC5,WAS,FCGR2B,INPP5D,CFL1,DNM2,PIK3R1,FCGR3B,RPS6KB2,PRKCA,RAC1,LIMK1,INPPL1,ARPC4,ACTR2,MAP2K1,VAV1,ARF6,PIK3R3,CFL2,SPHK2,PLPP1,PLCG1,CDC42,GAB2,PIP5K1C,PIP5K1A,ARPC1A,AKT1,PIK3CD,PIP5K1B,PLPP2,PLCG2,CRK,MAPK1,ARPC5L
Autoimmune thyroid disease	0.009	0.183	0.3807	0.7418	1.3447	50	GZMB,PRF1,CTLA4,HLA-B,HLA-DRA,HLA-DQB1,HLA-G,HLA-DRB5,HLA-E,CD86,HLA-A,CD28
Mitophagy	0.0096	0.183	0.3807	0.713	1.3169	68	GABARAPL1,GABARAP,GABARAPL2,CSNK2B,FIS1,BNIP3L,SQSTM1,CALCOCO2,HIF1A,BECN1,RRAS2,ATG5,TFEB,UBA52,USP15,TBC1D17,BCL2L1,ATG9B,MAPK9,UBB,ATF4,OPTN,ATG9A,AMBRA1,MFN1,TP53,MAPK8,TBC1D15,TOMM7,KRAS,RELA,PGAM5,RAB7A,EIF2AK3,E2F1,CSNK2A2,TFE3,SP1,CSNK2A1,ULK1,PINK1,NRAS,USP8,TBK1,RRAS
Hematopoietic cell lineage	0.0134	0.2322	0.3807	0.6788	1.2706	96	CD38,CD55,CD7,CD2,CD8B,IL7R,CD8A,CD3D,CD3E,HLA-DRA,HLA-DQB1,ITGA1,CD44,HLA-DRB5,ITGA4,CD59,CSF2,TFRC,IL11RA,IL7,FLT3LG,CD3G,ITGA2
Central carbon metabolism in cancer	0.015	0.2386	0.3807	0.7027	1.2961	70	LDHB,IDH2,MAP2K2,LDHA,SLC16A3,PGAM1,SLC7A5,HIF1A,PIK3R1,PTEN,G6PD,HK1,MAP2K1,TP53,MYC,NTRK1,SLC1A5,PIK3R3,KRAS,HK2,ERBB2,GLS,HKDC1,IDH1,SIRT6,TIGAR,PDK1,PFKL,FGFR1,AKT1,PIK3CD,PDGFRB,PFKM,NRAS,MAPK1,SIRT3,PDHA1,PFKP,FGFR2
Pancreatic cancer	0.0367	0.4789	0.2378	0.678	1.2576	76	STAT1,RAC2,BAK1,JAK1,TGFB1,RALBP1,BAX,RALA,STAT3,BCL2L1,E2F2,PIK3R1,MAPK9,RPS6KB2,CDKN2A,RAC1,SMAD4,RB1,MAP2K1,GADD45A,TP53,ARHGEF6,MAPK8,PIK3R3,KRAS,BAD,RELA,ERBB2,IKBKB,TGFB3,ARAF,SMAD2,CDC42,E2F1,DDB2,RALGDS,NFKB1,AKT1,SMAD3,PIK3CD
Synaptic vesicle cycle	0.0376	0.4789	0.2344	0.6746	1.2544	78	ATP6V0B,CLTB,ATP6V1G1,ATP6V1F,AP2S1,CLTA,ATP6V0D1,AP2M1,ATP6V0C,NAPA,DNM2,ATP6V1D,ATP6V1A,AP2A1,TCIRG1,ATP6V0A1,ATP6V1B2,ATP6V1G2,AP2A2,NSF,ATP6V0E1,ATP6V1H,ATP6V0A2,CACNA1A,ATP6V1C2,SLC1A7,STXBP1
Epithelial cell signaling in Helicobacter pylori infection	0.0391	0.4789	0.2311	0.6821	1.258	70	CCL5,CSK,NFKBIA,ATP6V0B,ATP6V1G1,ATP6V1F,ATP6V0D1,ATP6V0C,MAPK9,RAC1,ADAM10,ATP6V1D,ATP6V1A,JAM3,TCIRG1,MAPK8,ATP6V0A1,MAPK11,ATP6V1B2,RELA,CXCR1,ATP6AP1,IKBKB,PLCG1,ATP6V1G2,MAPK12,CXCL3,CDC42,ATP6V0E1,ATP6V1H,HBEGF,NFKB1,ATP6V0A2,ATP6V1C2,IKBKG,PLCG2
Viral myocarditis	0.0436	0.4789	0.2193	0.7008	1.2804	57	PRF1,CD55,HLA-B,RAC2,HLA-DRA,HLA-DQB1,HLA-G,HLA-DRB5,HLA-E,CD86,ACTG1,FYN,EIF4G3,HLA-A,BID,CD28,RAC1,CASP8
Linoleic acid metabolism	0.0445	0.4789	0.3218	-0.6403	-1.4561	28	PLA2G1B,PLA2G4C,JMJD7-PLA2G4B,CYP2E1
Long-term potentiation	0.0451	0.4789	0.2139	0.6811	1.2562	67	CAMK4,RPS6KA1,MAP2K2,PRKCB,RAP1B,PPP1CA,CALM3,RPS6KA3,PRKCA,ITPR1,ATF4,EP300,CREBBP,MAP2K1,PPP1CC,KRAS,PLCB2,CALM1,ARAF,PLCB3,CAMK2D,CACNA1C,PPP3CA,PPP3CB,NRAS,MAPK1
Vibrio cholerae infection	0.0554	0.525	0.1938	0.6982	1.2658	50	SEC61B,SEC61G,ATP6V0B,ATP6V1G1,ATP6V1F,ATP6V0D1,ACTG1,ATP6V0C,ERO1A,ARF1,ADCY3,PRKCA,ATP6V1D,ATP6V1A,TCIRG1,KDELR1,ATP6V0A1,SEC61A2,ATP6V1B2,ATP6AP1,PLCG1,GNAS,ATP6V1G2,ATP6V0E1,ATP6V1H,KDELR3,ATP6V0A2,ADCY9,ATP6V1C2
Bacterial invasion of epithelial cells	0.0616	0.525	0.1814	0.6693	1.2357	69	PXN,ARPC2,ARPC3,ARPC1B,CLTB,CLTA,RHOG,ILK,RHOA,ARPC5,ITGB1,ACTG1,HCLS1,DNM2,PIK3R1,MAD2L2,CBL,RAC1,ELMO1,ARPC4,ACTR2,PIK3R3,VCL,CDC42,ARPC1A,PIK3CD,ARHGEF26

Items per page:

1–20 of 50 items

of 3 pages

c10

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Proteasome	0	0.0001	0.6594	0.8716	1.5907	46	PSMB9,PSMB8,PSME2,PSMA2,PSME1,POMP,PSMB10,PSMA3,PSMB3,PSMB6,PSMB2,PSMA5,PSMA7,PSMA6,PSMA1,SEM1,PSMB1,PSMD9,PSMA4,PSMD7,PSMC5,ADRM1,PSMD8,IFNG,PSMC1,PSMC6,PSMD13,PSMB7,PSME4,PSMA8,PSMD3,PSMC4,PSMB4,PSMF1,PSMB5,PSMC2,PSMD4,PSMD1,PSMC3,PSMD6,PSME3,PSMD11
mRNA surveillance pathway	0.0001	0.0059	0.5384	0.7347	1.3971	98	CSTF3,NXT2,PPP1CA,SAP18,ETF1,PPP2CA,PPP2R2D,MAGOH,PAPOLA,UPF3B,PELO,RBM8A,PPP2R1A,RNPS1,GSPT1,PPP1CC,MAGOHB,PPP2R5C,DAZAP1,PYM1,SSU72,SMG7,PABPN1,PPP2R2A,PPP2R3C,NXT1,CPSF7,NCBP1,DDX19B,WDR33,NUDT21,ACIN1,CPSF3,CSTF2,UPF3A,CSTF2T,SRRM1,HBS1L,SMG1,CSTF1,DDX39B,PPP2R5B,SMG5,FUS,PABPC4,CLP1,EIF4A3,RNGTT,MSI2,FIP1L1,PCF11,CASC3,SMG6,ALYREF,CPSF2,DDX19A,CPSF4
Viral myocarditis	0.0001	0.0059	0.5384	0.7838	1.4561	57	PRF1,HLA-B,HLA-DRB1,HLA-DRA,HLA-A,HLA-DRB5,ACTG1,FYN,HLA-DQB1,HLA-DPB1,ACTB,ITGB2,SGCB,HLA-DPA1,HLA-G,RAC2,CD55,HLA-F,RAC1,EIF4G1,HLA-C,CASP3,CYCS,HLA-DQA1,EIF4G2,CASP8,ABL2,CD86,BID,HLA-E,HLA-DMA,RAC3,DAG1,HLA-DMB,CXADR
Cardiac muscle contraction	0.0003	0.0148	0.4985	0.7376	1.3917	83	TPM4,UQCR10,COX5A,COX6A1,COX8A,UQCRH,COX7B,COX4I1,COX6C,UQCRFS1,COX7A2,ATP2A2,UQCRQ,COX6B1,COX5B,COX7A2L,ATP1B3,UQCR11,TPM3,ASPH,UQCRC1,UQCRB,UQCRHL,CYC1,UQCRC2
Ribosome biogenesis in eukaryotes	0.003	0.1087	0.4317	0.7063	1.3313	79	NXT2,RAN,CSNK2A2,CSNK2B,NOP10,NOB1,NHP2,SPATA5,SNU13,UTP6,RPP25L,XRN2,SBDS,RMRP,REXO5,RIOK1,RBM28,NOP56,GNL2,RIOK2,UTP18,POP7,EIF6,RPP30,REXO2,TCOF1,GTPBP4,DKC1,NXT1,NMD3,GAR1,XRN1,AK6,UTP4,IMP3,XPO1,IMP4,EMG1,LSG1,POP5,POP4,NVL,RRP7A,GNL3,MDN1
Autoimmune thyroid disease	0.0034	0.1087	0.4317	0.7404	1.3583	50	GZMB,PRF1,HLA-B,HLA-DRB1,HLA-DRA,HLA-A,HLA-DRB5,HLA-DQB1,HLA-DPB1,CTLA4,HLA-DPA1,HLA-G,HLA-F,HLA-C,HLA-DQA1,CD86,HLA-E,HLA-DMA,TSHR,FAS,HLA-DMB,FASLG,CD28
Staphylococcus aureus infection	0.005	0.1357	0.407	0.6888	1.306	91	HLA-DRB1,HLA-DRA,FCGR3A,HLA-DRB5,HLA-DQB1,HLA-DPB1,ITGB2,HLA-DPA1,SELPLG,HLA-DQA1,KRT10,HLA-DMA,FCGR3B,ITGAM,HLA-DMB,FCGR2B
Protein export	0.0063	0.1512	0.407	0.8303	1.4084	23	SEC61B,SRP19,SRP14,SRP72,SPCS3,SEC61G,SPCS1,SEC11A,SRP9,OXA1L,SEC11C,SPCS2,SEC61A1,SRPRB,SRP68,SEC63,SEC62,HSPA5
Type I diabetes mellitus	0.0077	0.1636	0.407	0.7543	1.3615	41	GZMB,PRF1,HLA-B,HLA-DRB1,HLA-DRA,HLA-A,HLA-DRB5,HLA-DQB1,HLA-DPB1,ICA1,HLA-DPA1,HLA-G,HLA-F,HLA-C,IFNG,HSPD1,PTPRN2,HLA-DQA1,CD86,HLA-E,HLA-DMA,FAS,IL12A,HLA-DMB,FASLG
Long-term potentiation	0.0152	0.2895	0.3807	0.6923	1.2954	67	PRKCB,RAP1B,CALM3,PPP1CA,PRKACA,KRAS,RAF1,CALM1,ATF4,PRKACB,PPP1CC,PPP3CC,CAMK4,MAP2K2,CAMK2D,HRAS,RPS6KA1,RPS6KA3,PPP3CB,CALM2,MAP2K1,MAPK1,RAP1A
RNA degradation	0.0224	0.3425	0.3525	0.6702	1.2632	79	LSM1,BTG3,LSM2,LSM6,CNOT8,PFKP,LSM7,EXOSC4,CNOT7,CNOT4,HSPD1,LSM3,LSM8,EXOSC3,EXOSC2,LSM5,CNOT6L,EXOSC7,ENO1,PARN,XRN2,C1D,DIS3,DCPS,LSM4,TTC37,DHX36,CNOT3,ZCCHC7,XRN1,PNPT1,DCP2,WDR61,PAN2,PABPC4,CNOT1,EXOSC8,DCP1B,MPHOSPH6,TOB2,EDC4,HSPA9,EXOSC1
Taurine and hypotaurine metabolism	0.0265	0.3425	0.3525	-0.9161	-1.6909	11	GGT7,ADO,GGT1,CSAD
Nicotine addiction	0.0265	0.3425	0.2879	0.7314	1.3157	40	CACNA1A,CHRNA6,GABRD
Cytosolic DNA-sensing pathway	0.0266	0.3425	0.282	0.6878	1.2803	61	PYCARD,NFKBIA,IRF3,POLR2E,CCL4,ADAR,POLR3E,CCL5,IKBKB,IRF7,POLR2H,CGAS,IKBKG,POLR2L,POLR3B,CASP1,POLR1D,POLR2F,DDX58,POLR3GL,NFKBIB,POLR3H,POLR3F,POLR3K,POLR3A,POLR3C,TBK1,CXCL10,MAVS,ZBP1,POLR3D
Legionellosis	0.0277	0.3425	0.2765	0.7005	1.3012	57	PYCARD,MYD88,ITGB2,NFKBIA,RAB1B,CASP3,CYCS,HSPD1,ARF1,HSF1,BCL2L13,CASP8,RAB1A,SAR1B,SEC22B,NAIP,CASP1,CASP7,HSPA2,VCP,SAR1A,HBS1L,EEF1G,HSPA6,ITGAM,HSPA1L,IL12A,NFKB2,TLR5
Renin-angiotensin system	0.0289	0.3425	0.3525	-0.6397	-1.438	23	LNPEP,NLN,ATP6AP2,PRCP,CTSA
Antigen processing and presentation	0.0305	0.3425	0.2617	0.6782	1.272	69	CD74,HLA-B,HLA-DRB1,HLA-DRA,CD8B,CD8A,PSME2,B2M,TAP1,HLA-A,PSME1,HLA-DRB5,HLA-DQB1,HLA-DPB1,HLA-DPA1,KLRC1,HLA-G,HLA-F,CIITA,HLA-C,IFNG,CALR,KLRD1,HLA-DQA1,HSPA4,RFX5,HSP90AA1,RFXANK,TAPBP,HSPA2,HLA-E,CANX,PSME3,HLA-DMA,CTSS,HSPA5,HSPA6,HSPA1L,PDIA3,HLA-DMB
Central carbon metabolism in cancer	0.0325	0.3447	0.253	0.6734	1.2626	70	MTOR,IDH2,LDHB,PFKP,KRAS,SLC7A5,RAF1,PTEN,LDHA,PIK3CD,MAP2K2,NTRK1,PGAM1,HRAS,G6PD,HIF1A,PIK3CB,TP53,HK1,PDHB,SIRT6,SCO2,HKDC1,MAP2K1,MAPK1,PKM,MYC,PDHA1,TIGAR,IDH1,GLS,NRAS,GLS2,AKT2,PFKL
Basal transcription factors	0.0345	0.3466	0.2489	0.7176	1.3029	44	TAF10,TAF5,TBPL1,GTF2B,GTF2H5,TAF9,TAF4,TAF11,GTF2H1,GTF2A2,GTF2F2,TAF3,TAF6,TAF12,GTF2I,TAF15,GTF2H3,GTF2H2C,CDK7,GTF2E2,GTF2F1,ERCC2,GTF2A1,TAF2,ERCC3
Citrate cycle (TCA cycle)	0.0436	0.4059	0.225	0.7384	1.2916	30	IDH2,SUCLG1,DLD,SDHC,IDH3B,MDH2,IDH3A,SUCLA2,SDHD,SDHB,MDH1,CS,OGDH,SDHA,FH,IDH3G,PDHB,PCK2,PDHA1,IDH1,ACO2,ACLY,OGDHL

Items per page:

1–20 of 50 items

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c7

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Nicotine addiction	0.0001	0.0267	0.5188	-0.8385	-1.5446	40	CACNA1A
Autoimmune thyroid disease	0.0003	0.0303	0.4985	0.773	1.8626	50	HLA-B,GZMB,HLA-DRB1,HLA-DRA,CTLA4,HLA-DQB1,HLA-A,HLA-DPB1,HLA-G,HLA-DQA1,PRF1,HLA-DPA1,HLA-DOA,HLA-E,CD28,HLA-DRB5,IL4,IL10,HLA-F
Staphylococcus aureus infection	0.0014	0.0875	0.4551	0.5618	1.4844	91	HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-DPB1,HLA-DQA1,HLA-DPA1,HLA-DOA,PTAFR,HLA-DRB5,IL10
Type I diabetes mellitus	0.0024	0.0918	0.4317	0.7142	1.6442	41	HLA-B,GZMB,HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-A,HLA-DPB1,HLA-G,HLA-DQA1,PRF1,HLA-DPA1,HLA-DOA,HLA-E,CD28,HLA-DRB5
Gastric acid secretion	0.0024	0.0918	0.4317	-0.7184	-1.4075	76	ACTB,ATP1A1,ACTG1,CALM1,PRKACB,ATP1B1,GNAQ,KCNQ1,GNAS,PLCB3,GNAI3,SLC9A1,ITPR3,CA2,ADCY4,CALM2,ATP1B2,PLCB1,PRKCA
Graft-versus-host disease	0.004	0.1009	0.407	0.7107	1.6189	38	HLA-B,GZMB,HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-A,HLA-DPB1,KLRC1,HLA-G,HLA-DQA1,PRF1,HLA-DPA1,HLA-DOA,HLA-E,CD28,HLA-DRB5
Allograft rejection	0.005	0.1009	0.407	0.7022	1.5807	35	HLA-B,GZMB,HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-A,HLA-DPB1,HLA-G,HLA-DQA1,PRF1,HLA-DPA1,HLA-DOA,HLA-E,CD28,HLA-DRB5,IL4,IL10,HLA-F
Gap junction	0.0051	0.1009	0.407	-0.692	-1.3773	88	TUBB,TUBA1B,TUBA1A,TUBA1C,PRKACB,GNAQ,GNAS,TUBB2A,TUBB4B,RAF1,PLCB3,GNAI3,MAPK7,MAP2K5,ADRB1,CDK1,ITPR3,PDGFB,TUBB4A,ADCY4,HRAS,MAP2K2,MAPK1,PLCB1,SOS1,PRKCA
Arachidonic acid metabolism	0.0054	0.1009	0.407	-0.7253	-1.3888	58	LTC4S,GGT1,TBXAS1,CBR1,CBR3,PTGES3,EPHX2,GPX3,ALOX12B,CYP2U1,CYP2J2,CYP2E1,AKR1C3,PTGS1,PLA2G12A
Maturity onset diabetes of the young	0.0058	0.1009	0.407	-0.8268	-1.4292	26	HHEX,HES1
Amphetamine addiction	0.0058	0.1009	0.407	-0.7065	-1.3756	69	FOS,FOSB,CALM1,PRKACB,JUN,PPP3R1,PPP1CC,HDAC1,GNAS,ATF6B,STX1A,PPP3CB,PPP3CA,CALM2,HDAC2,ARC,CREB1,PRKCA,PRKCG,CACNA1C,SLC18A2
Asthma	0.0186	0.2963	0.3525	0.6918	1.4863	28	HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-DPB1,HLA-DQA1,HLA-DPA1,HLA-DOA,HLA-DRB5,IL4,IL10
Viral myocarditis	0.0257	0.3782	0.3525	0.5402	1.3437	57	HLA-B,HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-A,HLA-DPB1,FYN,HLA-G,CD55,HLA-DQA1,PRF1,HLA-DPA1,HLA-DOA,HLA-E,CD28,HLA-DRB5,BID,CASP8,HLA-F
Intestinal immune network for IgA production	0.0285	0.3895	0.3525	0.5686	1.3407	45	HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-DPB1,HLA-DQA1,HLA-DPA1,HLA-DOA,CXCR4,CD28,HLA-DRB5,ICOSLG,IL4,IL10,ICOS,TNFRSF13C
Systemic lupus erythematosus	0.0321	0.4085	0.3218	0.5711	1.379	51	HLA-DRB1,HLA-DRA,HLA-DQB1,HLA-DPB1,HLA-DQA1,HLA-DPA1,HLA-DOA,CD28,HLA-DRB5,IL10
Malaria	0.037	0.4411	0.2489	-0.7154	-1.348	50	TNF,KLRB1,ITGAL,PECAM1,TGFB1,KLRK1,THBS3,ITGB2,CD40LG,CD81,CD40,CR1,KLRC4-KLRK1,ICAM1,MYD88,LRP1,IL18,THBS4,CD36,IL12A,TGFB3
Antigen processing and presentation	0.0413	0.4646	0.3218	0.4873	1.2545	69	HLA-B,HLA-DRB1,HLA-DRA,CD74,HLA-DQB1,HLA-A,TAP1,HLA-DPB1,KLRC1,HLA-G,HLA-DQA1,HLA-DPA1,HLA-DOA,B2M,HLA-E,CD8A,HLA-DRB5,PSME2,TAP2,KIR2DL4,HLA-F
Pertussis	0.0494	0.5237	0.209	-0.654	-1.2812	76	FOS,TNF,CALM1,CFL1,JUN,TICAM1,RELA,RHOA,ITGB2,CASP1,GNAI3,MAPK14,MAPK13,NLRP3,IL23A,CASP3,LY96,TRAF6,CALM2,ITGA5,C5,TICAM2,ITGAM,C1QA,MAPK1,MYD88,ITGB1,NFKB1,NOS2,CD14,C3,C1R,IL12A
Dilated cardiomyopathy	0.0536	0.525	0.1978	-0.632	-1.26	95	ACTB,TNF,ACTG1,PRKACB,TGFB1,TPM3,ITGB7,ITGA3,GNAS,TPM1,ITGA1,ITGA4,ADRB1,CACNA2D2,ADCY4,CACNB3,ITGA5,TNNC1
Hypertrophic cardiomyopathy	0.0581	0.525	0.19	-0.6316	-1.257	90	ACTB,TNF,ACTG1,TGFB1,TPM3,ITGB7,ITGA3,PRKAB1,PRKAA1,PRKAG2,TPM1,ITGA1,ITGA4,CACNA2D2,CACNB3,ITGA5,TNNC1,PRKAB2,ITGB1,CACNA1C,ITGA7,TGFB3,CACNB1,PRKAG1,SGCB,ITGA6

Items per page:

1–20 of 50 items

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c3

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Cardiac muscle contraction	0	0.0086	0.5573	0.7653	1.3594	83	COX7C,COX5A,UQCRH,COX8A,TPM4,UQCRB,COX6C,COX6B1,COX7A2L,COX4I1,UQCRFS1,UQCR10,COX5B,COX7A2,COX6A1,COX7B,UQCRC1,UQCR11,CYC1,UQCRC2,UQCRQ,CACNA2D4,ATP1B3,SLC9A6
Proteasome	0.0003	0.0244	0.4985	0.811	1.4082	46	PSMB9,PSMB8,SEM1,PSMA1,PSMB3,PSME1,PSME2,PSMB1,PSMB10,POMP,PSMB4,PSMC5,PSMA6,PSMB6,PSMC3,PSMF1,PSMA4,PSMB2,PSMD3,PSMD7,PSMD4,PSME3,PSMA7,PSMA2,PSMD9,PSMC1,PSMC2,PSMA5,PSMD6,PSMD13,ADRM1,PSMD8,PSMB5,PSMD1,PSMB7,PSMC6
Primary immunodeficiency	0.0007	0.0412	0.4773	0.8104	1.3831	37	CD3D,TAP1,JAK3,LCK,CD3E,CD8A,IL2RG,ADA,ZAP70,PTPRC,RFX5,CD8B,TNFRSF13C,ICOS,IKBKG,CD79A,RFXAP,TAP2
Nicotine addiction	0.001	0.0467	0.4551	-0.655	-1.6985	40	GABRD
Vibrio cholerae infection	0.0065	0.1885	0.407	0.7448	1.3012	50	SEC61B,ACTG1,ATP6V1G1,GNAS,ARF1,ATP6V0B,ACTB,ATP6V1F,ERO1A,ATP6V0C,ATP6AP1,ATP6V0D1,ATP6V0A2,SEC61G,ATP6V1D,SEC61A2,ATP6V1C1,ATP6V1A,KDELR2,PRKACB,TCIRG1,ATP6V1B2,ATP6V0E1,ATP6V1E1,ATP6V0A1,PLCG2,KDELR1,SLC12A2,PRKACA,ADCY3
mRNA surveillance pathway	0.0067	0.1885	0.407	0.6886	1.2313	98	PABPC1,PPP1CC,NUDT21,PPP2R5C,SSU72,RNPS1,PPP1CA,PABPC1L,GSPT1,ALYREF,PPP2R3C,PPP1CB,MSI2,CSTF2T,PPP2CA,SMG1,ACIN1,DDX19A,NXT1,PPP2R1A,HBS1L,GSPT2,SAP18,SYMPK,NCBP2,PYM1,RBM8A,UPF2,PPP2R5E,PPP2R2A,PELO,WDR33,PPP2R2D,UPF3A,SMG6,CASC3,EIF4A3,CSTF2,GLE1,ETF1,FIP1L1,PNN,CPSF1,PPP2R5A,SRRM1,CSTF1,CPSF6,PPP2R1B,WDR82,CPSF2
Morphine addiction	0.0076	0.1885	0.407	0.6886	1.2292	91	PDE3B,PDE4B,PDE4D,GNG5,GNAS,PDE7B,GNAI2,GNG10,PDE7A,PRKCB,ARRB2,GNB2,GNGT2,GNB1,ARRB1,PDE1B,PRKACB,GRK2,GRK4,GNG4,PDE4A,GRK3,GNG2
Collecting duct acid secretion	0.0079	0.1885	0.3807	0.8102	1.3554	27	ATP6V1G1,ATP6V1F,ATP6V0C,ATP6V0D1,ATP6V0A2,ATP6V1D,ATP6V1C1,ATP6V1A,SLC12A7,TCIRG1,ATP6V1B2,ATP6V0E1,ATP6V1E1,ATP6V0A1
Glycolysis / Gluconeogenesis	0.0104	0.2185	0.3807	0.7133	1.2586	66	GAPDH,LDHB,LDHA,ACSS1,TPI1,PGK1,DLAT,GALM,PGAM1,ALDOA,PDHB,DLD,PCK2,MINPP1,AKR1A1,PGM2,ENO1,PFKP,PFKM,ALDOC,ADH5,ALDH3A2,HK2,PDHA1,ADPGK,HKDC1
Fc gamma R-mediated phagocytosis	0.0116	0.2203	0.3807	0.6872	1.2282	96	RAC2,ARPC2,ARPC3,ARPC1B,LAT,WAS,CFL1,PLPP1,PTPRC,PIK3CD,ARPC5,INPP5D,PRKCB,WASF2,ASAP1,ACTR2,VASP,MARCKSL1,VAV1,PIK3R1,PIP5K1A,GSN,FCGR3A,INPPL1,PIK3R3,ARPC4,AKT2,RPS6KB1,BIN1,RAC1,MAP2K1,GAB2,LIMK1,ARPC1A,PLA2G6,RAF1,FCGR2B,RPS6KB2,PIP5K1C,PIP5K1B,JMJD7-PLA2G4B,SPHK2,CFL2,MAPK3,PRKCD,PLCG2,ARF6,AKT3,DNM2,ACTR3,ARPC5L,LIMK2,PIK3CA
Porphyrin and chlorophyll metabolism	0.0141	0.2337	0.3807	0.7402	1.2771	42	HMOX1,UROD,COX15,EARS2,GUSB,COX10,PPOX,CPOX,HMOX2,ALAD,UROS,FXN,ALAS1
Phototransduction	0.0148	0.2337	0.3807	0.7792	1.3099	28	CALM3,GNB1,CALM2,PDE6B,SLC24A1,PDE6G,CALM1
Viral myocarditis	0.0263	0.3372	0.282	0.7086	1.2461	57	HLA-B,PRF1,RAC2,CD55,FYN,ACTG1,HLA-A,HLA-DRA,HLA-E,ACTB,EIF4G3,CD28,HLA-DRB1,EIF4G2,HLA-G,HLA-DQB1,EIF4G1,CYCS,HLA-DOA,ABL2,RAC1,CASP3,HLA-DPA1,HLA-DPB1
PD-L1 expression and PD-1 checkpoint pathway in cancer	0.0271	0.3372	0.2765	0.6756	1.2034	89	CD3D,LCK,CD3E,ZAP70,LAT,EML4,CSNK2B,JAK1,STAT1,TICAM1,BATF,MYD88,PIK3CD,CD247,CSNK2A1,NFKBIA,STAT3,CD3G,CD28,MAP3K3,MAP2K3,NRAS,RASGRP1,PDCD1,HIF1A,NFATC3,PRKCQ,IKBKB,KRAS,PTEN,PIK3R1,IKBKG,CD274,PIK3R3,AKT2,RPS6KB1,MAP2K1,NFATC1,PPP3R1,JAK2,RAF1,RPS6KB2,MAPK11,NFKBIB,NFATC2,CSNK2A2,MAPK3
Mitophagy	0.0282	0.3372	0.2713	0.6938	1.2278	68	GABARAP,GABARAPL2,FIS1,CSNK2B,EIF2AK3,USP8,CSNK2A1,UBB,UBA52,CALCOCO2,ATF4,TBC1D15,TAX1BP1,TOMM7,NBR1,NRAS,BECN1,HIF1A,CITED2,RAB7A,GABARAPL1,RPS27A,KRAS,RRAS2,FOXO3,BNIP3L,ATG9B,BNIP3,CSNK2A2,RHOT2,TFE3,OPTN,TBC1D17,E2F1,FUNDC1,JUN,RHOT1,MAPK9,UBC,TP53,SQSTM1,USP15
Autoimmune thyroid disease	0.0284	0.3372	0.2713	0.7137	1.2469	50	CTLA4,HLA-B,GZMB,PRF1,HLA-A,HLA-DRA,HLA-E,CD28,HLA-DRB1,HLA-G,HLA-DQB1,HLA-DOA,HLA-DPA1,HLA-DPB1,IL10
Protein export	0.0372	0.4027	0.2413	0.7781	1.2819	23	SEC61B,OXA1L,SRP14,SPCS1,SEC11A,SRP19,SRP72,SEC61G,SEC61A2,SPCS3,SRP54,SEC11C,SRPRB,SEC62,SRP9,SPCS2,SRP68
Synaptic vesicle cycle	0.0382	0.4027	0.2311	0.6755	1.2006	78	ATP6V1G1,ATP6V0B,ATP6V1F,AP2S1,CLTA,ATP6V0C,NAPA,ATP6V0D1,ATP6V0A2,AP2M1,ATP6V1D,CLTB,STX2,ATP6V1C1,ATP6V1A,NSF,AP2A1,TCIRG1,ATP6V1B2,ATP6V0E1,ATP6V1E1,CLTC,ATP6V0A1,STX1A
Bacterial invasion of epithelial cells	0.0412	0.4121	0.2221	0.685	1.2139	69	ARPC2,ARPC3,ACTG1,ARPC1B,RHOG,RHOA,ACTB,PIK3CD,ARPC5,CLTA,HCLS1,WASF2,CBL,ACTR2,CLTB,ELMO1,PIK3R1,PIK3R3,ARPC4,RAC1,CD2AP,CTNNB1,MAD2L2,ELMO2,CLTC,ARPC1A
Citrate cycle (TCA cycle)	0.0542	0.4343	0.1958	0.7386	1.2475	30	IDH2,SDHC,MDH2,DLAT,IDH3G,SUCLG1,CS,SDHB,ACO2,PDHB,SDHD,MDH1,DLD,PCK2,DLST,IDH1,OGDH,ACLY,PDHA1

Items per page:

1–20 of 50 items

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c1

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Nicotine addiction	0	0.0001	0.675	-0.915	-1.7961	40	CACNA1A
Mineral absorption	0.0027	0.259	0.4317	0.628	1.5577	60	FTH1,MT2A,MT1X,MT1F,ATP1B3,FTL,ATP7B,ATP1A4,VDR,MT1E,ATP1B1
Autoimmune thyroid disease	0.01	0.459	0.3807	0.6145	1.471	50	HLA-B,HLA-DRB1,HLA-G,HLA-A,HLA-DQB1,HLA-F,GZMB,HLA-DRB5,HLA-E,HLA-DRA
Graft-versus-host disease	0.0118	0.459	0.3807	0.6645	1.5167	38	HLA-B,HLA-DRB1,HLA-G,HLA-A,HLA-DQB1,HLA-F,GZMB,HLA-DRB5,HLA-E,HLA-DRA
Cardiac muscle contraction	0.012	0.459	0.3807	0.5151	1.3623	83	UQCRH,ATP1B3,COX7C,COX7B,CACNA2D4,UQCRB,TPM4,COX7A2,COX7A2L,COX5B,ATP1A4,COX6A1,COX8A,ATP1B1,COX6B1,UQCRQ,UQCR10,UQCRHL,UQCRFS1,COX4I1,TPM3,CACNA1F,SLC9A6,UQCRC2
Type I diabetes mellitus	0.0224	0.6773	0.3525	0.6307	1.4442	41	HLA-B,HLA-DRB1,HLA-G,HLA-A,HLA-DQB1,HLA-F,GZMB,HLA-DRB5,HLA-E,HLA-DRA
Maturity onset diabetes of the young	0.0248	0.6773	0.3525	-0.7726	-1.4052	26	GCK,NR5A2,NKX2-2,HES1
Allograft rejection	0.0321	0.7654	0.3218	0.6088	1.3735	35	HLA-B,HLA-DRB1,HLA-G,HLA-A,HLA-DQB1,HLA-F,GZMB,HLA-DRB5,HLA-E,HLA-DRA
ECM-receptor interaction	0.0413	0.8771	0.3218	0.4598	1.2279	88	ITGB1,COL1A1,ITGB7,SV2A,ITGA10,HMMR,LAMA3,LAMC3,GP6,ITGA3,ITGA2,THBS3,CD44
Amphetamine addiction	0.0568	0.9868	0.2066	-0.62	-1.3024	69	FOS,PRKACB,PPP3R1,FOSB,PPP1CC,CREB1,HDAC2,CAMK2D,CREB3L4,CREB3L2,CAMK4,JUN,CACNA1C,ATF6B,PPP3CB,PRKCA,CAMK2G,CREB3L1,ATF2,CALM3,HDAC1
mRNA surveillance pathway	0.0631	0.9868	0.19	-0.5821	-1.2745	98	FUS,FIP1L1,PPP2CA,PPP1CC,GLE1,PCF11,SMG6,PPP2R5D,PPP2R5A,SYMPK,PELO,PPP2R5E,EIF4A3,CPSF3,NCBP2,TARDBP,CPSF7,CPSF6,PPP2R2B,CPSF2,DDX19A,WDR82,DDX39B,UPF3A,CSTF2T,ACIN1,CPSF1,SMG7,RNGTT,NUDT21,PAPOLG,CASC3,PPP2R1B,PAPOLA,NCBP1,PPP2R1A,GSPT2,MAGOHB,DDX19B,NXT2,PNN,UPF2,PPP2R2A,SSU72,CSTF1,NXT1,SMG1,PABPN1
Nitrogen metabolism	0.0657	0.9868	0.2878	0.7538	1.4491	17	GLUL,GLUD1,CPS1,CA8,CA5B,CA13
PD-L1 expression and PD-1 checkpoint pathway in cancer	0.0711	0.9868	0.1814	-0.5855	-1.2637	89	LAT,LCK,FOS,CD4,PPP3R1,PRKCQ,NFATC1,ZAP70,CD28,PTPN6,HIF1A,CD3G,MAPK14,MAP2K6,STAT3,PLCG1,NFKBIE,CSNK2A1,IFNGR1,CD274,PIK3CB,MAPK13,KRAS,JAK1,TRAF6,NFATC2,JUN,CD3D,PIK3R2,TICAM1,CD3E,PIK3CD,IFNG,AKT2,RPS6KB2,MAP3K3,PPP3CB,RELA,RASGRP1
Viral protein interaction with cytokine and cytokine receptor	0.0754	0.9868	0.2878	0.4365	1.1576	98	TNFRSF14,TNFRSF1B,CXCR4,IL18R1,IL10RA,CXCR3,CCL4,CCR10,CCR4,CCR6,CCR2,ACKR4,IL24,CXCL13,CCL3,IL10RB,CCL4L2,CCL5,CCR8,XCL1,CCL20
Fatty acid degradation	0.0804	0.9868	0.1767	-0.6565	-1.3043	43	CPT1A,ACADVL,CYP2U1,ACSL5,ADH5,HADHA,ALDH7A1,EHHADH,ACSL4,ALDH9A1,ACADSB,CPT1C,ALDH3A2,ACSL1,ACSL3,CPT1B,HADHB,GCDH
Malaria	0.0884	0.9868	0.1657	-0.6326	-1.2778	50	ITGAL,ITGB2,KLRB1,CD40LG,IL10,TGFB3,CD40,IFNG,CD81,PECAM1,THBS1,KLRC4-KLRK1,CSF3
Fc gamma R-mediated phagocytosis	0.0971	0.9868	0.1511	-0.5642	-1.232	96	LAT,PTPRC,ACTR3,CDC42,ACTR2,ARPC5,PLCG1,MARCKSL1,SPHK2,NCF1,VAV1,ARPC5L,PLPP1,CFL2,PIK3CB,PRKCD,DNM2,RAC2,CFL1,FCGR2B,PIK3R2,PIP5K1A,PIK3CD,AKT2,ARF6,RPS6KB2,ARPC2,INPPL1,ACTR3B,PRKCA
Ascorbate and aldarate metabolism	0.0982	0.9868	0.1608	-0.6987	-1.306	30	ALDH7A1,ALDH9A1,ALDH3A2
Citrate cycle (TCA cycle)	0.0982	0.9868	0.1608	-0.6989	-1.3064	30	MDH1,ACO1,DLAT,PCK2,IDH3B,FH,OGDH,PDHA1,PDHB,SDHD,SUCLA2,SUCLG1,DLD,SUCLG2,CS,SDHA,DLST,SDHB,IDH3G,PC,ACLY,ACO2
Small cell lung cancer	0.1231	0.9913	0.2878	0.4309	1.141	92	ITGB1,PIK3R1,NFKBIA,CDKN1A,GADD45B,E2F3,E2F2,BIRC3,BCL2,BAX,NOS2,LAMA3,LAMC3,PTEN,CDK2,ITGA3,CDKN1B,AKT1,ITGA2,RXRA,BCL2L1,FHIT,MAX,DDB2,GADD45A

Items per page:

1–20 of 50 items

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c4

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Nicotine addiction	0	0.0008	0.6105	0.8881	1.6646	40	CACNA1A,GABRD
Proteasome	0.0001	0.0077	0.5384	0.8351	1.594	46	PSMB9,PSME1,PSME2,PSMB8,PSMB10,PSMA1,POMP,PSMA5,SEM1,PSMB2,PSMB6,PSMA4,PSMB3,IFNG,PSMA2,PSMD9,PSMB4,PSMD8,PSMB1,PSMB7,PSME4,PSMA7,PSMD13,ADRM1,PSMC4,PSMF1,PSMD7,PSMC5,PSMC1,PSMA6,PSMC3,PSMA3,PSMC6,PSMC2,PSMD4,PSMD14,PSMB5
Cytosolic DNA-sensing pathway	0.0011	0.0674	0.4551	0.7501	1.4698	61	CCL5,PYCARD,IRF7,ADAR,AIM2,NFKBIA,POLR2L,IKBKG,CCL4,POLR1D,CGAS,IKBKB,ZBP1,POLR2K,POLR3GL,DDX58,IKBKE,IRF3,TBK1,POLR2F,NFKBIB,CXCL10,POLR3E,CHUK,RIPK3,POLR2E,POLR3K,POLR3D
Autoimmune thyroid disease	0.0015	0.0674	0.4551	0.7755	1.4983	50	HLA-B,HLA-A,HLA-DRA,HLA-DRB1,HLA-DPA1,HLA-E,HLA-G,HLA-DPB1,GZMB,HLA-F,HLA-C,PRF1,HLA-DRB5,CD28,TSHR,HLA-DQB1,FASLG
Graft-versus-host disease	0.0018	0.0674	0.4551	0.8055	1.4936	38	HLA-B,HLA-A,HLA-DRA,HLA-DRB1,HLA-DPA1,HLA-E,HLA-G,HLA-DPB1,GZMB,HLA-F,HLA-C,IFNG,PRF1,HLA-DRB5,CD28,KLRD1,HLA-DQB1,FASLG
Antigen processing and presentation	0.0023	0.0689	0.4317	0.7314	1.4479	69	HLA-B,B2M,CD74,TAP1,PSME1,PSME2,HLA-A,CD8A,HLA-DRA,HLA-DRB1,HLA-DPA1,CD8B,HLA-E,HLA-G,HLA-DPB1,HLA-F,HLA-C,TAPBP,IFNG,CTSS,HLA-DRB5,NFYC,KLRD1,TAP2,IFI30,HLA-DQB1,HSP90AA1,RFX5
Cardiac muscle contraction	0.0027	0.0689	0.4317	0.7208	1.4419	83	UQCR10,COX7A2,COX5A,TPM4,UQCR11,COX6C,COX7B,COX8A,COX6B1,UQCRQ,COX7C,UQCRFS1,UQCRH,COX5B,COX4I1,COX7A2L,COX6A1,ATP1B3,UQCRB,CYC1,CACNA2D4,ATP2A2,UQCRC2,TPM3
Viral myocarditis	0.0029	0.0689	0.4317	0.7501	1.4648	57	HLA-B,HLA-A,HLA-DRA,HLA-DRB1,HLA-DPA1,RAC2,CD55,HLA-E,HLA-G,HLA-DPB1,HLA-F,FYN,HLA-C,ACTG1,PRF1,EIF4G3,HLA-DRB5,CD28,BID,RAC1,HLA-DQB1,ITGB2,DMD,HLA-DOB,CYCS,ITGAL,ACTB
Primary immunodeficiency	0.0042	0.0891	0.407	0.7746	1.431	37	TAP1,CD8A,IL7R,ADA,CD8B,LCK,ICOS,CD3D,CD3E,JAK3,IL2RG,ORAI1,IKBKG,TAP2,ZAP70,RFX5,CIITA,RFXANK
Type I diabetes mellitus	0.0058	0.1115	0.407	0.7638	1.4371	41	HLA-B,HLA-A,HLA-DRA,HLA-DRB1,HLA-DPA1,HLA-E,HLA-G,HLA-DPB1,GZMB,HLA-F,HSPD1,HLA-C,IFNG,PRF1,HLA-DRB5,CD28,HLA-DQB1,FASLG,PTPRN2,FAS,HLA-DOB
Maturity onset diabetes of the young	0.0095	0.1476	0.3807	-0.7757	-1.6623	26	HES1,NR5A2,NKX2-2,GCK
Morphine addiction	0.0098	0.1476	0.3807	0.6714	1.3477	91	PDE3B,ARRB2,PDE4B,GNG5,PDE4D,PRKCB,GRK2,GNG10,ADCY7,GNAI2,GNB2,PDE7A,GNAS,GNG2,GRK3,CACNA1A,GNAO1,GNB1,ADCY4,GNAI1,PDE7B,GNAI3,ADCY9,GNB4,PDE1B
Regulation of lipolysis in adipocytes	0.01	0.1476	0.3807	0.7115	1.3862	54	PDE3B,PIK3R1,ADCY7,GNAI2,PIK3CD,GNAS,TSHR,ADCY4,AKT2,AKT1,MGLL,GNAI1,ABHD5,GNAI3,ADCY9,IRS2,PLIN1,ADRB1,PIK3CA,PRKACB,PRKACA
Hematopoietic cell lineage	0.0123	0.1683	0.3807	0.6634	1.338	96	CD8A,HLA-DRA,CD2,IL7R,HLA-DRB1,CD38,HLA-DPA1,CD55,CD8B,ITGA1,HLA-DPB1,CD3D,CD3E,ITGA4,CD7,CD37,HLA-DRB5,FLT3LG,IL7,CD3G,CSF2,TFRC,HLA-DQB1,ITGA2
Allograft rejection	0.0177	0.2251	0.3525	0.7536	1.3865	35	HLA-B,HLA-A,HLA-DRA,HLA-DRB1,HLA-DPA1,HLA-E,HLA-G,HLA-DPB1,GZMB,HLA-F,HLA-C,IFNG,PRF1,HLA-DRB5,CD28,HLA-DQB1,FASLG
Non-small cell lung cancer	0.0443	0.5083	0.2193	0.6508	1.2955	72	PIK3R1,JAK3,EML4,STK4,PRKCB,KRAS,BAD,KIF5B,PIK3CD,NRAS,BAK1,E2F1,GRB2,STAT5B,MAP2K1,CDKN2A,CDK6,E2F3,RXRB,E2F2,GADD45B,RB1,PLCG2,AKT2,ARAF,SOS1,AKT1,RET,HRAS,BAX
Vasopressin-regulated water reabsorption	0.0514	0.5083	0.209	0.703	1.3345	44	ARHGDIB,DYNLL1,RAB11A,GNAS,RAB5C,AQP3,DCTN6,ARHGDIA,DYNC1I2,DYNC1H1,STX4,DCTN5,CREB3L2,DCTN2,ADCY9,CREB3,CREB1,DYNC1LI2,RAB5A,CREB3L4,DCTN1,PRKACB,PRKACA
Synaptic vesicle cycle	0.0561	0.5083	0.1938	0.637	1.2696	78	ATP6V1F,ATP6V0B,AP2S1,CLTB,ATP6V1G1,ATP6V0E1,ATP6V0C,AP2M1,ATP6V0D1,CACNA1A,DNM2,ATP6V1C2,STX2,CLTA,ATP6V1D,STXBP1,NAPA,TCIRG1,STX1A
Inflammatory mediator regulation of TRP channels	0.0582	0.5083	0.1882	0.6205	1.2515	98	PIK3R1,PTGER4,PPP1CA,PRKCB,ADCY7,CALM1,PIK3CD,GNAS,CALM3,TRPV2,ITPR1,MAP2K3,PRKCQ,MAPK11,ADCY4,NTRK1,PLCG2,MAP2K6,CALML4,ADCY9,PRKCD,TRPV1,MAPK12,PPP1CC,ITPR2,JMJD7-PLA2G4B,PIK3CA,PRKACB,PLCG1,PRKCH,PRKACA,PRKCE,CALM2,PRKCA,MAPK9
GABAergic synapse	0.0586	0.5083	0.1882	0.6259	1.2545	89	GNG5,GABARAP,PRKCB,GNG10,ADCY7,GNAI2,GNB2,GABARAPL2,GNG2,ABAT,CACNA1A,GNAO1,GNB1,ADCY4,GNAI1,SLC38A1,GNAI3,ADCY9,GNB4,CACNA1D,GNG12,SLC12A5,GNGT2,SLC38A5,GLS,GNB5,PRKACB,PRKACA,PRKCA

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c5

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Hypertrophic cardiomyopathy	0.0048	0.4903	0.407	-0.6859	-1.3507	90	ACTB,ACTG1,TNF,ITGB7,TPM3,ITGA4,ITGA1,ATP2A3,TPM4,ITGA5,ITGB1,ACE,TGFB1,CACNB1,PRKAB2,PRKAB1,PRKAG2,CACNA1C,CACNA2D2,TPM2,EMD,PRKAA1
Amphetamine addiction	0.0055	0.4903	0.407	-0.719	-1.3809	69	FOS,CALM1,FOSB,PPP1CA,PRKACB,HDAC1,ATF6B,PPP3R1,JUN,CAMK2G,STX1A,SIRT1,CREB3L2,PPP1CC,CREB1,DDC,PRKCG,CACNA1C,SLC18A2,CALM3,PPP3CA,CALM2,PPP3CC,PPP1CB,GNAS
Cardiac muscle contraction	0.0101	0.4903	0.3807	-0.6845	-1.3396	83	COX4I1,ATP1A1,TPM3,COX6B1,ATP1B1,UQCRB,UQCR10,ATP2A3,TPM4,FXYD2,COX8A,COX5B,UQCRC2,UQCRC1,COX7C,CACNB1,COX6A1,COX6C,ATP1B2,CACNA1C,CYC1,CACNA2D2,TPM2
Autoimmune thyroid disease	0.0128	0.4903	0.3807	0.5721	1.3979	50	HLA-B,CTLA4,GZMB,HLA-G,HLA-DQB1,HLA-A,HLA-DRB1,HLA-DRB5,CGA
Dilated cardiomyopathy	0.0133	0.4903	0.3807	-0.6696	-1.3191	95	ACTB,ACTG1,TNF,ITGB7,TPM3,PRKACB,ITGA4,ITGA1,ATP2A3,TPM4,ITGA5,ITGB1,TGFB1,CACNB1,ADRB1,CACNA1C,CACNA2D2,TPM2,EMD
Renin-angiotensin system	0.0154	0.4903	0.3807	-0.81	-1.377	23	ATP6AP2,LNPEP,ACE,PRCP,PREP,THOP1
Fatty acid degradation	0.0222	0.6045	0.3525	-0.7315	-1.3455	43	CPT1A,ACADVL,ACSL6,ECHS1,ADH5,ACSL5,ACSL3,ACAA2,ALDH9A1,HADHB,ACADSB,ECI2,ALDH3A2,CPT1B,HADHA,HADH,ACADS,EHHADH,ACOX3,ACOX1,ACSBG2
Arrhythmogenic right ventricular cardiomyopathy	0.0389	0.852	0.2344	-0.6606	-1.2817	77	ACTB,ACTG1,ITGB7,CTNNA1,ITGA4,ITGA1,ATP2A3,LEF1,ITGA5,ITGB1,CACNB1,JUP,CACNA1C,CACNA2D2
Bacterial invasion of epithelial cells	0.0491	0.852	0.209	-0.6639	-1.275	69	ACTB,ACTG1,ACTR3,ARPC5,ARPC2,CDC42,RHOA,CLTA,HCLS1,CTNNA1,ILK,ACTR2,RAC1,CLTC,SRC,ITGA5,ARPC4,ITGB1,CRK,PIK3CD,ACTR3B,DNM2,ARPC1B,PIK3R1,DNM1,SHC1,CBL,ELMO3,WASF2,VCL,PTK2,CLTCL1,DOCK1,GAB1,PIK3R2,WASF1,CRKL,ARPC5L,ELMO1,ARPC3,PIK3R3,DNM3,PIK3CB,PIK3CA
Synaptic vesicle cycle	0.0641	0.852	0.1798	-0.6443	-1.2517	78	ATP6V0A1,CLTA,VAMP2,STX3,AP2M1,CLTC,AP2S1,ATP6V0E1,ATP6V1G1,CPLX1,STX1A,RAB3A,DNM2,AP2B1,ATP6V1D,DNM1,SLC18A2,UNC13B,ATP6V1G2,AP2A1,ATP6V1B2,ATP6V1F,ATP6V1E1,SLC32A1,SNAP25,CACNA1A,CLTCL1,SLC6A9,AP2A2,ATP6V0D1,DNM3,ATP6V1A,ATP6V1C1,STXBP1
Vasopressin-regulated water reabsorption	0.0671	0.852	0.1814	-0.6938	-1.2799	44	RAB5B,PRKACB,DYNC2H1,VAMP2,ARHGDIA,STX4,RAB11A,ARHGDIB,RAB5A,DCTN2,RAB11B,CREB3L2,DYNC1LI1,CREB1,DCTN4,DCTN1
Graft-versus-host disease	0.0682	0.852	0.2878	0.5241	1.2285	38	HLA-B,GZMB,HLA-G,HLA-DQB1,HLA-A,HLA-DRB1,HLA-DRB5,HLA-DRA,CD28
Type I diabetes mellitus	0.0685	0.852	0.2878	0.5102	1.2141	41	HLA-B,GZMB,HLA-G,HLA-DQB1,HLA-A,HLA-DRB1,HSPD1,HLA-DRB5
Glycolysis / Gluconeogenesis	0.0719	0.852	0.1709	-0.6518	-1.2492	66	PKM,FBP1,ALDOA,PGM2,ADH5,GAPDH,ENO2,ALDH9A1,BPGM,ALDH3A2,GPI,ENO1,HK1,PGAM1,PDHA1,TPI1,ACSS2,LDHB,PFKP,DLAT,PDHB
DNA replication	0.0766	0.852	0.1709	-0.7151	-1.2894	36	POLA1,RNASEH2C,MCM2,MCM4,MCM3,RNASEH1,DNA2,RPA2,RPA1,RFC5,RPA3,MCM7,RFC1,POLD4,PCNA,MCM5,LIG1
Tryptophan metabolism	0.078	0.852	0.1682	-0.6924	-1.2693	42	CAT,ECHS1,KYAT3,ALDH9A1,ALDH3A2,HADHA,HADH,EHHADH,DLST,DDC,TPH1,DHTKD1,KMO,ALDH8A1,CYP1A1,AANAT,HAAO,ALDH1B1,KYAT1,IL4I1,GCDH
Gastric acid secretion	0.0847	0.852	0.1552	-0.6349	-1.2301	76	ACTB,ACTG1,CALM1,ATP1A1,GNAI3,PRKACB,PLCB2,ATP1B1,KCNQ1,CAMK2G
Peroxisome	0.0932	0.852	0.1464	-0.6239	-1.2212	82	SCP2,CAT,ACSL6,PRDX5,ACSL5,PEX26,MPV17L2,PECR,EPHX2,CROT,ACSL3,HSD17B4,ECI2,ABCD2,PAOX,AGPS,SLC25A17,PEX13,PEX11G,EHHADH,ACOT8,PHYH,DECR2,PXMP2,ACOX3,PEX19,ACOX1,NUDT7,PXMP4,PEX3,MLYCD,PEX16,PEX11B,ABCD3,MPV17,PEX5,HACL1,DHRS4,PEX10,ACAA1,PIPOX,ABCD1,PEX7,PRDX1,PEX12,PEX1
Nucleotide excision repair	0.1065	0.852	0.1404	-0.6598	-1.2231	46	ERCC5,ERCC1,CDK7,GTF2H2,CUL4A,XPA,GTF2H4,RAD23B,DDB1,CUL4B,RPA2,RPA1,RFC5,RPA3,GTF2H1,RFC1,MNAT1,POLD4,PCNA,CETN2,LIG1,RAD23A,RBX1
Non-homologous end-joining	0.1129	0.852	0.1464	-0.8028	-1.2483	13	XRCC5,XRCC6,DCLRE1C,PRKDC,POLM,MRE11,LIG4,RAD50,POLL,FEN1

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c11

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Proteasome	0	0.0006	0.6273	0.8722	1.7088	46	PSMB9,PSMB8,PSME1,POMP,PSMB10,PSME2,SEM1,PSMA2,PSMA5,PSMB3,PSMB4,PSMD7,PSMA1,PSMA7,PSMB6,PSMB2,PSMC6,PSMA3,PSMA4,PSMB7,PSMB1,PSMD8,IFNG,PSMD4,PSMC1,PSMD12,PSMA6,PSME3,PSMD13,PSME4,ADRM1,PSMC5,PSMD11,PSMD1,PSMB5,PSMC3,PSMC2,PSMD3
Cardiac muscle contraction	0.0002	0.0218	0.5188	0.7351	1.5193	83	COX5B,UQCR11,UQCRFS1,COX7A2,UQCR10,CYC1,COX4I1,COX6A1,UQCRB,COX6C,COX7B,COX6B1,UQCRQ,SLC9A1,COX7C,ATP2A2,UQCRC2,UQCRH,COX8A,COX5A,COX7A2L,UQCRC1,TPM4,UQCRHL,ATP1B3,ATP1A3
Maturity onset diabetes of the young	0.0018	0.1118	0.4551	-0.8238	-1.7627	26	HES1,HHEX
Staphylococcus aureus infection	0.003	0.1445	0.4317	0.6724	1.3996	91	HLA-DRA,SELPLG,FCGR3A,ITGB2,KRT10,HLA-DRB1,HLA-DRB5,IL10,HLA-DQB1,FCGR3B,KRT18,ITGAM,HLA-DPB1,FCGR2B,C5,ITGAL
Nicotine addiction	0.0066	0.2538	0.407	0.7561	1.4545	40	CACNA1A,GABRR2,GABRD,CHRNB2
Viral myocarditis	0.0091	0.2894	0.3807	0.7032	1.4151	57	HLA-B,PRF1,HLA-A,CD55,HLA-DRA,FYN,HLA-E,HLA-G,ITGB2,ACTG1,CASP8,CYCS,HLA-DRB1,HLA-DRB5,CD28,ACTB,HLA-F,EIF4G1,CASP3,HLA-DQB1,CASP9,HLA-C,RAC2,EIF4G3,CD80,HLA-DPB1,RAC1
Autoimmune thyroid disease	0.0161	0.4394	0.3525	0.6969	1.3813	50	GZMB,HLA-B,PRF1,CTLA4,HLA-A,HLA-DRA,HLA-E,HLA-G,HLA-DRB1,HLA-DRB5,CD28,HLA-F,IL10,HLA-DQB1,HLA-C
Mineral absorption	0.0323	0.6113	0.2664	0.6612	1.3336	60	MT1E,MT2A,FTL,MT1X,FTH1,HMOX2,MT1F,HMOX1,ATP1B3,CYBRD1,ATP1A3,MT1G,ATOX1,SLC11A2,FXYD2,SLC39A4,SLC46A1,ATP2B1,SLC26A6,VDR,SLC31A1,STEAP1
Cysteine and methionine metabolism	0.0342	0.6113	0.2617	0.6859	1.3594	50	LDHB,KYAT1,PHGDH,MDH2,ENOPH1,PSAT1,IL4I1,MDH1,MAT2B,MRI1,BCAT1,APIP,LDHA,MPST,AHCY,TST,CTH,MTR,BCAT2,SRM,GCLM,GCLC,AHCYL1
Ribosome biogenesis in eukaryotes	0.037	0.6113	0.245	0.6341	1.3065	79	XRN2,WDR43,REXO2,POP4,NOP10,CSNK2B,RPP38,SNU13,WDR75,RPP40,IMP3,NOL6,MDN1,GNL3,NOP56,FBL,RRP7A,RAN,AK6,GNL2,REXO1,UTP15,RPP30,RIOK1,CSNK2A2,EIF6,HEATR1,NHP2,UTP18,DKC1,WDR36,NXT2,IMP4,SBDS,EMG1,WDR3,NOB1,TBL3,LSG1,DROSHA,RCL1,XPO1,GTPBP4,CSNK2A1,XRN1,GNL3L
Citrate cycle (TCA cycle)	0.0403	0.6113	0.2489	0.7425	1.3725	30	IDH2,SUCLG1,SDHA,MDH2,PDHA1,SDHC,MDH1,FH,SDHB,PCK2,DLST,ACO2,ACLY,DLAT,IDH3A,OGDH,IDH3B,OGDHL,PDHB,SUCLG2
Steroid hormone biosynthesis	0.0408	0.6113	0.3218	-0.4945	-1.2827	61	CYP7B1,HSD17B12,STS,SRD5A1,HSD11B1L,LRTOMT,HSD17B7,HSD17B1,HSD17B8,HSD17B6
Cytosolic DNA-sensing pathway	0.0435	0.6113	0.228	0.6479	1.3082	61	AIM2,NFKBIA,POLR2E,DDX58,POLR1D,POLR2L,POLR2F,IRF7,NFKBIB,POLR2K,POLR3G,IRF3,RELA,PYCARD,ADAR,CCL4,IKBKE,POLR3GL,RIPK3,CCL5,POLR3D,TBK1,POLR3A,POLR2H
Mitophagy	0.0448	0.6113	0.2221	0.6425	1.3126	68	GABARAP,FIS1,RPS27A,GABARAPL1,GABARAPL2,CSNK2B,TBC1D17,TOMM7,RRAS2,BECN1,TFEB,UBA52,ATG9A,BNIP3L,USP15,UBB,RELA,ULK1,CSNK2A2,PGAM5,NRAS,RRAS,ATF4,KRAS,TBK1,RAB7A,AMBRA1,USP8,ATG5,OPTN
RIG-I-like receptor signaling pathway	0.0514	0.6258	0.2066	0.6357	1.2998	69	AZI2,NFKBIA,DDX58,CYLD,CASP8,IRF7,NFKBIB,CASP10,TRIM25,ATG12,TANK,TRADD,IRF3,PIN1,RNF125,RELA,TRAF3,SIKE1,IKBKE,IL12A,MAPK12,ISG15,TBK1,DHX58
Taste transduction	0.0524	0.6258	0.3218	-0.4443	-1.2185	85	ITPR3,TAS2R31,HTR3A,TAS1R3,ENTPD2,KCNK5
Tryptophan metabolism	0.0634	0.657	0.19	0.6809	1.3214	42	KYAT1,AFMID,IL4I1,ALDH9A1,ASMT,GCDH,DLST,HADH,ECHS1,HADHA,EHHADH,DHTKD1,KMO,ACAT2,HAAO,CAT,DDC,ALDH8A1,ACAT1,DLD
B cell receptor signaling pathway	0.0641	0.657	0.2878	-0.4303	-1.1601	79	FOS,LYN,VAV3,LILRB1,VAV2,CD19,BLNK,BTK,CD22,PLCG2,SOS1,CD79A,CR2,GSK3B,AKT3,CD72,JUN,CD79B,CHUK,RAF1,CD81,PIK3R3,PTPN6,SOS2,BCL10,PPP3CA
Folate biosynthesis	0.0654	0.657	0.1938	0.7414	1.3426	26	AKR1B1,DHFR,PCBD1,PCBD2,MOCS2,GCH1,PTS,QDPR,SPR,CBR1,DHFR2
Type I diabetes mellitus	0.0798	0.7536	0.1682	0.6734	1.3009	41	GZMB,HLA-B,PRF1,HLA-A,HLA-DRA,HLA-E,HLA-G,HLA-DRB1,HLA-DRB5,CD28,IFNG,HLA-F,HSPD1,HLA-DQB1,HLA-C,IL12A,CD80,ICA1,HLA-DPB1

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c9

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Nicotine addiction	0	0.0003	0.6436	-0.9469	-2.0926	40	CHRNA6
Maturity onset diabetes of the young	0.0002	0.0167	0.5188	-0.9272	-1.8729	26	HES1
Taste transduction	0.0013	0.0817	0.4551	-0.6003	-1.533	85	PLCB3,PLCB2,PRKACB,ENTPD2,ADCY4,CHRM3,PLCB1,P2RY1
Proteasome	0.0028	0.1333	0.4317	0.7837	1.4633	46	PSMB9,PSMB8,PSME2,PSMB2,IFNG,PSMA5,PSMB10,SEM1,PSMB6,PSME1,PSMA2,POMP,PSMA1,PSMB3,PSMD6,PSMA7,PSMB4,PSMD3,PSMA3,PSMA4,PSMD13,PSMC3,PSMF1,PSMC2,ADRM1,PSMD7,PSMB1,PSMA6,PSMD8,PSMD4,PSMC6,PSMC4,PSMD9,PSME3,PSMC5,PSMB7
Morphine addiction	0.0062	0.2367	0.407	0.6907	1.3677	91	PDE3B,PDE4B,GNG4,GNB1,PDE4D,PRKCB,PDE4A,ARRB2,GRK3,ADCY7,GNG2,GNB2,GNG5,GNG10,GRK2,GNB4,PDE7B,PDE7A,GNAO1,PDE2A,GNG12,PRKACA,PDE1B,GNAS,GNB5
Viral myocarditis	0.0084	0.2661	0.3807	0.7435	1.4261	57	HLA-B,FYN,HLA-A,HLA-G,CD40,HLA-F,EIF4G3,CYCS,HLA-DRA,CD55,RAC2,CCND1,HLA-DRB1,HLA-E,HLA-DMB,HLA-DPA1,HLA-C,PRF1,CD80,CD40LG,CD28,CASP9,EIF4G1,RAC1,SGCB,ABL2,HLA-DPB1,CXADR,DMD,HLA-DOA,CAV1,ABL1,ICAM1,HLA-DMA,HLA-DRB5,EIF4G2,CASP3
Antigen processing and presentation	0.0263	0.6294	0.3525	0.7043	1.3728	69	HLA-B,TAP1,B2M,CD74,PSME2,HLA-A,HLA-G,IFNG,CD8A,IFI30,HLA-F,CD8B,HLA-DRA,PSME1,TAP2,RFXANK,HLA-DRB1,HLA-E,HLA-DMB,HSPA2,HLA-DPA1,HLA-C,KLRD1,TAPBP,RFXAP,HLA-DPB1,CD8B2,HLA-DOA,HSPA6,CIITA,HLA-DMA,CTSB,PSME3,HLA-DRB5
Primary immunodeficiency	0.0296	0.6294	0.3525	0.7651	1.3847	37	TAP1,ICOS,CD8A,CD40,CD8B,IL2RG,JAK3,CD79A,TAP2,RFXANK,LCK,CD40LG,ORAI1,ADA,CD3D,IL7R,DCLRE1C,RFXAP,CD8B2,CIITA,PTPRC
Basal cell carcinoma	0.0297	0.6294	0.3525	-0.5413	-1.3175	63	WNT10A,POLK,PTCH2,DDB2,GADD45G,TCF7L1,WNT1,WNT2B,CDKN1A,GSK3B,BAX,DVL3,APC
Cardiac muscle contraction	0.0381	0.6367	0.2413	0.6585	1.2994	83	UQCR10,COX5A,UQCRQ,CACNA2D4,COX7C,COX7A2,COX7B,COX7A2L,TPM4,ATP1B3,CYC1,ATP2A2,UQCR11,COX6C,UQCRFS1,COX8A,COX4I1,COX6B1,UQCRH,ASPH,COX6A1,UQCRC1,COX5B,MYL3,TNNC1,FXYD2
Type I diabetes mellitus	0.0398	0.6367	0.245	0.7407	1.3695	41	HLA-B,HLA-A,HLA-G,IFNG,HSPD1,HLA-F,HLA-DRA,PTPRN2,HLA-DRB1,FASLG,HLA-E,HLA-DMB,GZMB,HLA-DPA1,HLA-C,PRF1,CD80,CD28,HLA-DPB1,IL2,HLA-DOA,CPE
Graft-versus-host disease	0.04	0.6367	0.2489	0.7477	1.3569	38	HLA-B,HLA-A,HLA-G,IFNG,HLA-F,HLA-DRA,HLA-DRB1,FASLG,HLA-E,HLA-DMB,GZMB,HLA-DPA1,HLA-C,PRF1,CD80,KLRD1,CD28,HLA-DPB1,IL2,HLA-DOA
Autoimmune thyroid disease	0.0453	0.6663	0.228	0.7062	1.3349	50	HLA-B,HLA-A,HLA-G,CD40,HLA-F,HLA-DRA,HLA-DRB1,FASLG,HLA-E,HLA-DMB,GZMB,HLA-DPA1,HLA-C,PRF1,CD80,TG,TSHR,CD40LG,CD28,HLA-DPB1,IL2,HLA-DOA
Carbohydrate digestion and absorption	0.0569	0.7316	0.3218	-0.5499	-1.2776	46	ATP1B1,PLCB3,PLCB2,CACNA1D,ATP1A4,ATP1A1,PLCB1,AKT1,SLC37A4,PIK3CA,AMY2B,PIK3R3,PIK3R1,ATP1B2,AKT3
Cytosolic DNA-sensing pathway	0.0615	0.7316	0.1919	0.6686	1.2865	61	CCL5,IRF7,CCL4,CGAS,POLR3H,NFKBIA,NFKBIB,AIM2,POLR3G,ADAR,POLR2L,POLR3A,PYCARD,CCL4L2,CXCL10,POLR2K,POLR2E,IKBKB,IKBKE,CHUK,POLR3E,POLR3D,IRF3,TBK1,MAVS,POLR2H,POLR1C,DDX58,ZBP1,IKBKG,TREX1
Histidine metabolism	0.0631	0.7316	0.2878	-0.7401	-1.4521	22	CARNS1,AMDHD1,CARNMT1,ALDH9A1
Cysteine and methionine metabolism	0.0651	0.7316	0.1882	0.691	1.3062	50	BCAT1,LDHA,PHGDH,MDH1,MDH2,PSAT1,LDHB,IL4I1,ADI1,MAT2B,SMS,AMD1,MPST,CDO1,GOT2,SRM,GCLM,APIP,TST,GSS,MRI1,MAT2A,GOT1,DNMT3A,MTR,KYAT3
mRNA surveillance pathway	0.0724	0.7516	0.1696	0.62	1.2401	98	PABPN1,NUDT21,PPP2R5C,SMG7,PPP1CC,RNPS1,SMG5,PPP2CA,PPP2R2D,RBM8A,SSU72,HBS1L,PYM1,GSPT1,CSTF2T,PPP1CA,ACIN1,PPP2R3C,WDR33,SRRM1,ALYREF,MAGOH,SMG1,RNMT,NCBP2,SAP18,NXF1,WDR82,PPP2CB,PNN,UPF2,CSTF2,UPF3A,NXT1,PAPOLA,CSTF1,PPP1CB,UPF3B,PPP2R5D,SYMPK,CASC3,PPP2R5E,PABPC1L,PPP2R5A,CPSF7,ETF1,FIP1L1,MAGOHB,CPSF2,DDX19A,PABPC1,CLP1,UPF1,CPSF4
Ribosome biogenesis in eukaryotes	0.0783	0.7516	0.1657	0.6365	1.2516	79	RAN,NOP10,REXO2,CSNK2A2,GTPBP4,RPP25,WDR36,NOP58,XRN1,NOB1,SBDS,RIOK1,NMD3,POP1,BMS1,CSNK2B,GNL3,SNU13,HEATR1,GAR1,NXF1,WDR3,NHP2,EMG1,WDR43,IMP3,NXT1,RPP30,DKC1,POP7,RRP7A,IMP4,EIF6,UTP14C,UTP14A,GNL2,XRN2,MPHOSPH10,TCOF1,NVL,SPATA5,RCL1,UTP15,RMRP,UTP4,XPO1,NOP56,RPP25L,UTP6
Gastric acid secretion	0.0787	0.7516	0.2878	-0.4682	-1.1564	76	ATP1B1,PLCB3,PLCB2,PRKACB,KCNQ1,ATP1A4,ATP1A1,CALM1,CAMK2B,ADCY4,CHRM3,PLCB1,ACTB,CAMK2D,GNAI3,SLC9A1,ITPR1,ATP1B2

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c2

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Amphetamine addiction	0.0002	0.0337	0.5188	-0.7476	-1.4263	69	FOS,FOSB,CALM1,PPP1CA,PRKACB,PPP1CC,HDAC1,HDAC2,PPP1CB,PPP3R1,GNAS,PRKACA,PPP3CA,ATF6B,CAMK2D,CALM3,SLC18A2,ARC,CAMK2G,PPP3CC,CREB3L2
Ascorbate and aldarate metabolism	0.0004	0.0337	0.4985	-0.8358	-1.4623	30	ALDH3A2,ALDH9A1,UGDH,ALDH1B1,AKR1A1
Dilated cardiomyopathy	0.0014	0.0872	0.4551	-0.7009	-1.3637	95	ACTB,ACTG1,TNF,ITGA1,TPM3,ITGB7,PRKACB,ITGA4,CACNB1,ATP2A3,SGCB,GNAS,PRKACA,TGFB1,ITGA2,TPM4,ADCY3,DAG1,CACNA2D2,TNNC1,ITGB4,TGFB3,TTN,ITGB1,ADCY7,TPM1,ITGA5,PLN,CACNB2,TGFB2
Insulin secretion	0.0018	0.0872	0.4551	-0.6996	-1.3564	86	PRKACB,PLCB2,ATP1A1,FXYD2,KCNN4,GNAS,PRKACA,PLCB1,KCNMB3,ATF6B,VAMP2,PLCB3,RAB3A,CAMK2D,ATP1B2,ADCY3,ATP1B1,CAMK2G,ITPR3,CREB3L2,GCK
Hypertrophic cardiomyopathy	0.0025	0.0951	0.4317	-0.6943	-1.3491	90	ACTB,ACTG1,TNF,ITGA1,TPM3,ITGB7,ITGA4,PRKAB2,CACNB1,ACE,ATP2A3,SGCB,TGFB1,ITGA2,TPM4,PRKAG1,DAG1,CACNA2D2,TNNC1,ITGB4,TGFB3,TTN,ITGB1,TPM1,ITGA5,PRKAB1,CACNB2,TGFB2
Vibrio cholerae infection	0.0033	0.1018	0.4317	-0.7561	-1.3968	50	ACTB,ACTG1,PRKACB,PDIA4,SEC61G,KCNQ1,SEC61B,ATP6V1G1,TCIRG1,SEC61A1,ATP6V0A1,ATP6AP1,GNAS,PLCG1,PRKACA,ATP6V1E1,ATP6V1G2,KDELR1,ATP6V1E2,ATP6V1F,ATP6V1A,ATP6V0E2,ARF1,ADCY3,KDELR2,ATP6V1B2,ATP6V0B,ATP6V1C1,ATP6V1D
Glycolysis / Gluconeogenesis	0.0037	0.1018	0.4317	-0.7106	-1.3523	66	PKM,GAPDH,ENO1,ALDOA,GPI,PGAM1,ENO2,PFKL,ADH5,TPI1,FBP1,PGK1,HK1,ALDH3A2,PGM2,LDHA,ALDOC,ALDH9A1,DLD,PGM1,PDHA1,MINPP1,GCK,ALDH1B1,ACSS1,AKR1A1
Nicotine addiction	0.005	0.1087	0.407	0.6674	1.6454	40	CHRNA6,CACNA1A,GABRD
Renin-angiotensin system	0.0051	0.1087	0.407	-0.8406	-1.4232	23	ATP6AP2,ACE,LNPEP,THOP1,PREP
Gastric acid secretion	0.0068	0.1298	0.407	-0.6989	-1.3428	76	ACTB,ACTG1,CALM1,PRKACB,PLCB2,ATP1A1,KCNQ1,GNAS,PRKACA,PLCB1,PLCB3,CAMK2D,CALM3,ATP1B2,ADCY3,ATP1B1,CAMK2G
Salivary secretion	0.0113	0.1956	0.3807	-0.6687	-1.3004	93	CALM1,PRKACB,PLCB2,ATP1A1,ADRB2,FXYD2,KCNN4,GNAS,PRKACA,PLCB1,VAMP2,PLCB3,CALM3,ATP1B2,ADCY3,PRH1,ATP1B1,ITPR3,ADCY7,ATP2B4,ATP2B1
Taste transduction	0.0131	0.2066	0.3807	-0.6705	-1.3024	85	KCNK5,PRKACB,PLCB2,PRKACA,PLCB1,PLCB3,TAS2R14,ITPR3,TAS2R50,TAS2R5,TAS1R3,TAS2R43,P2RY4,SCNN1A,TAS2R4,TAS2R30
Autoimmune thyroid disease	0.015	0.2066	0.3807	0.5878	1.5111	50	HLA-B,HLA-DRB1,HLA-G,HLA-DRB5,HLA-A,GZMB,CTLA4,HLA-DQB1,HLA-E,HLA-DRA,CGA,IL4,TPO,FAS
Synaptic vesicle cycle	0.0151	0.2066	0.3807	-0.678	-1.3049	78	CLTA,AP2B1,ATP6V1G1,TCIRG1,ATP6V0A1,AP2S1,ATP6V1E1,ATP6V1G2,VAMP2,ATP6V1E2,RAB3A,ATP6V1F,ATP6V1A,CPLX1,ATP6V0E2,CLTC,SLC18A2,STX3,ATP6V1B2,AP2M1,ATP6V0B,ATP6V1C1,NSF,ATP6V1D,DNM2,AP2A2,CLTCL1,UNC13A,UNC13B,SYT1,ATP6V1G3,CLTB,NAPA,ATP6V0D1
Protein export	0.0301	0.3492	0.282	-0.788	-1.334	23	SRPRA,SPCS1,SRP68,SEC63,SEC61G,SEC61B,SEC61A1,SPCS3,SEC62,HSPA5,SPCS2,SRP9,SRP14,SRP54,SRP72
Citrate cycle (TCA cycle)	0.0305	0.3492	0.2765	-0.7577	-1.3256	30	MDH1,DLST,ACO1,PC,MDH2,SUCLG1,IDH2,ACLY,CS,ACO2,FH,SUCLA2,IDH3G,SDHC,DLD,PDHA1,SUCLG2
Cardiac muscle contraction	0.0369	0.3492	0.2378	-0.6563	-1.272	83	TPM3,ATP1A1,COX8A,CACNB1,COX6B1,ATP2A3,FXYD2,COX4I1,UQCRC2,UQCRC1,COX6A1,SLC9A6,COX5A,COX7A2,TPM4,ATP1B2,UQCR11,ATP1B1,CACNA2D2,ASPH,TNNC1,SLC9A7,COX5B,CYC1
Long-term potentiation	0.0417	0.3492	0.225	-0.6707	-1.2772	67	CALM1,RAP1A,PPP1CA,PRKACB,PPP1CC,PLCB2,RPS6KA1,PPP1CB,PPP3R1,PRKACA,PLCB1,PPP3CA,PLCB3,CAMK2D,CALM3,NRAS,RPS6KA2,CAMK2G,MAPK1,PPP3CC,ITPR3,RAF1,MAPK3,HRAS,GRIN2D,RAPGEF3,ITPR2,CREBBP,BRAF,KRAS,CALM2,ITPR1
Ether lipid metabolism	0.0432	0.3492	0.225	-0.7041	-1.2981	46	CHPT1,PLD1,PAFAH2,PAFAH1B3,PLPP2,PLA2G6,PLD3,CEPT1,PLPP1,AGPS,PAFAH1B1,ENPP2,PLA2G4B,TMEM86B,LPCAT4,GDPD1,SELENOI,JMJD7-PLA2G4B,PLD2,LPCAT1
Nitrogen metabolism	0.0449	0.3492	0.3218	0.7628	1.5131	17	GLUL,CA5B,GLUD1,CA6

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c8

Showing top 50 pathways by padj in descending order. Use 'Download the entire data' button to download all pathways.


Nicotine addiction	0.0001	0.0109	0.5573	-0.8792	-1.6304	40	CACNA1A
Autoimmune thyroid disease	0.0001	0.0133	0.5188	0.8061	1.857	50	GZMB,HLA-B,PRF1,HLA-A,HLA-DRB1,HLA-DQB1,CTLA4,HLA-E,HLA-DPB1,HLA-G,HLA-F,HLA-DRB5,HLA-DRA,HLA-DQA1,HLA-DOA
Viral myocarditis	0.0004	0.02	0.4985	0.7168	1.699	57	HLA-B,PRF1,CD55,HLA-A,HLA-DRB1,HLA-DQB1,FYN,HLA-E,HLA-DPB1,HLA-G,HLA-F,HLA-DRB5,HLA-DRA,HLA-DQA1,EIF4G3,BID,CASP3,HLA-DOA,CASP8,CD28,ABL1,DAG1,RAC1
Maturity onset diabetes of the young	0.0004	0.02	0.4985	-0.9128	-1.5763	26	HHEX,HES1,NEUROG3
Type I diabetes mellitus	0.0011	0.0406	0.4551	0.7792	1.7175	41	GZMB,HLA-B,PRF1,HLA-A,HLA-DRB1,HLA-DQB1,HLA-E,HLA-DPB1,HLA-G,HLA-F,HLA-DRB5,HLA-DRA,HLA-DQA1,HSPD1,HLA-DOA,PTPRN,IL12A,CD28,PTPRN2
Phototransduction	0.0061	0.1947	0.407	-0.8253	-1.4404	28	CALM1,PDE6G,GUCY2D,CALM3,PDE6B,CALM2
Allograft rejection	0.0093	0.255	0.3807	0.7644	1.6466	35	GZMB,HLA-B,PRF1,HLA-A,HLA-DRB1,HLA-DQB1,HLA-E,HLA-DPB1,HLA-G,HLA-F,HLA-DRB5,HLA-DRA,HLA-DQA1,HLA-DOA,IL12A,CD28
Asthma	0.0252	0.6014	0.3525	0.713	1.4467	28	HLA-DRB1,HLA-DQB1,HLA-DPB1,HLA-DRB5,HLA-DRA,HLA-DQA1,FCER1G,HLA-DOA
Graft-versus-host disease	0.0319	0.6776	0.3218	0.6558	1.429	38	GZMB,HLA-B,PRF1,HLA-A,HLA-DRB1,HLA-DQB1,HLA-E,KLRC1,HLA-DPB1,HLA-G,HLA-F,HLA-DRB5,HLA-DRA,HLA-DQA1,KIR2DL1,HLA-DOA
Pyruvate metabolism	0.0398	0.7594	0.2489	-0.7171	-1.3578	47	GLO1,DLAT,ACACB,LDHB,ADH5,ACYP1,MDH1,FH,ACAT2,PDHA1,ALDH9A1,PKM,ALDH1B1,ACSS2
Taste transduction	0.0458	0.795	0.3218	0.4989	1.2703	85	P2RY1,ITPR3,PDE1B,TAS2R20,CACNA1C,ADCY4,PRKACA,KCNK5
Glycolysis / Gluconeogenesis	0.0537	0.8553	0.209	-0.6631	-1.3024	66	DLAT,ENO2,PGM1,LDHB,ADH5,ALDOC,GPI,BPGM,PGM2,MINPP1,PDHA1,FBP1,ALDH9A1,ENO1,ALDOA,PGAM1,HK1,PKM,ALDH1B1,GAPDH
Tyrosine metabolism	0.0996	0.9947	0.1563	-0.7124	-1.3006	36	FAH,GOT2,ADH5,MIF,IL4I1,LRTOMT
Amphetamine addiction	0.108	0.9947	0.1429	-0.6244	-1.2295	69	FOS,FOSB,CALM1,PRKACB,HDAC1,PPP1CA,PPP3R1,PPP1CB,CREB3L3,PRKCA,HDAC2,CREB1,CALM3,PPP3CC,CREB3,CREB3L4,CREB3L2,CALM2,SLC18A2,ARC,GNAS,CAMK2G,JUN,PPP1CC,ATF6B,PRKCB,PPP3CB
Endocrine and other factor-regulated calcium reabsorption	0.1308	0.9947	0.1301	-0.6342	-1.2165	53	PRKACB,ATP1A1,ATP1B1,PRKCA,DNM1,PLCB1,AP2M1,DNM2,AP2B1,ADCY6,DNM3,GNAQ,ATP1A3,CLTCL1,GNAS,RAB11A,AP2A1,PLCB2,PLCB3,PRKCB,CLTB
Thyroid hormone synthesis	0.1313	0.9947	0.1275	-0.6105	-1.2119	74	PRKACB,ATP1A1,ATP1B1,CANX,HSPA5,HSP90B1,CREB3L3,PRKCA,PLCB1,CREB1,ITPR2,PDIA4,ADCY3,ADCY6,GNAQ,ATP1A3,TTF2,CREB3,PAX8,CREB3L4,CREB3L2,GPX3
Metabolism of xenobiotics by cytochrome P450	0.1354	0.9947	0.1256	-0.6061	-1.1988	72	GSTP1,MGST3,GSTA4,GSTM3,ADH5,GSTM1,AKR7A2,GSTK1,DHDH,CBR1,CYP2F1,CYP2D6
Viral protein interaction with cytokine and cytokine receptor	0.1392	0.9947	0.1204	-0.5786	-1.1808	98	XCL1,CXCR3,XCL2,CCL4L2,CCL3L1,TNFSF14,IL2,TNFRSF10A,TNF,TNFRSF1A,IL2RG,IL10RB,IL6R
Morphine addiction	0.1424	0.9947	0.2492	0.4646	1.1815	91	PDE4B,PDE3B,PDE4D,GNG2,GRK5,PDE1B,GNG4,ADCY4,GNB4,GRK3,ARRB2,PRKACA,PDE7B,ADCY9,PDE4A,PDE7A,GNG10
Fanconi anemia pathway	0.1425	0.9947	0.1238	-0.6294	-1.2096	54	RPA1,CENPS-CORT,FANCE,FANCD2,MUS81,CENPS,EME2,ERCC4,RAD51C,RPA2,PMS2,TOP3A,HES1,TELO2,FAAP100,FAN1,ATRIP,FANCI,POLN,RPA4,SLX1A,UBE2T,ERCC1,TOP3B,FANCB,SLX1B,WDR48,REV3L,RMI1,POLK,FANCM,FANCF

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GSEA (all seurat_clusters)

Heatmap

Pathways for all seurat_clusters.

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DotPlot

Pathways for all seurat_clusters.

Image loading error!

Showing the first job only. Check the workdir for information of other jobs if any.

# Generated by pipen_runinfo v0.9.3
# Lang: R
R version 4.3.3 (2024-02-29)
Platform: x86_64-conda-linux-gnu (64-bit)
Running under: Debian GNU/Linux 12 (bookworm)

Matrix products: default
BLAS/LAPACK: /opt/conda/lib/libopenblasp-r0.3.30.so;  LAPACK version 3.12.0

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[10] LC_TELEPHONE=C         LC_MEASUREMENT=C.UTF-8 LC_IDENTIFICATION=C   

time zone: Etc/UTC
tzcode source: system (glibc)

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] biopipen.utils_0.3.2 ggplot2_3.5.2        tidyr_1.3.1         
 [4] dplyr_1.1.4          tidyseurat_0.8.0     ttservice_0.5.3     
 [7] Seurat_5.3.0         SeuratObject_5.2.0   sp_2.2-0            
[10] rlang_1.1.6         

loaded via a namespace (and not attached):
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  [3] splines_4.3.3               later_1.4.4                
  [5] bitops_1.0-9                tibble_3.3.0               
  [7] polyclip_1.10-7             enrichit_0.0.4             
  [9] fastDummies_1.7.5           lifecycle_1.0.4            
 [11] doParallel_1.0.17           globals_0.18.0             
 [13] lattice_0.22-7              MASS_7.3-60.0.1            
 [15] magrittr_2.0.3              plotly_4.11.0              
 [17] httpuv_1.6.16               sctransform_0.4.2          
 [19] spam_2.11-1                 spatstat.sparse_3.1-0      
 [21] reticulate_1.43.0           cowplot_1.2.0              
 [23] pbapply_1.7-4               RColorBrewer_1.1-3         
 [25] abind_1.4-5                 zlibbioc_1.48.0            
 [27] Rtsne_0.17                  GenomicRanges_1.54.1       
 [29] purrr_1.1.0                 ggraph_2.2.1               
 [31] BiocGenerics_0.48.1         RCurl_1.98-1.17            
 [33] tweenr_2.0.3                evmix_2.12                 
 [35] circlize_0.4.16             GenomeInfoDbData_1.2.11    
 [37] IRanges_2.36.0              S4Vectors_0.40.2           
 [39] ggrepel_0.9.6               irlba_2.3.5.1              
 [41] listenv_0.9.1               spatstat.utils_3.1-5       
 [43] iNEXT_3.0.2                 MatrixModels_0.5-4         
 [45] goftest_1.2-3               RSpectra_0.16-2            
 [47] scRepertoire_2.2.1          spatstat.random_3.4-1      
 [49] fitdistrplus_1.2-4          parallelly_1.45.1          
 [51] codetools_0.2-20            DelayedArray_0.28.0        
 [53] xml2_1.4.0                  ggforce_0.5.0              
 [55] tidyselect_1.2.1            shape_1.4.6.1              
 [57] farver_2.1.2                viridis_0.6.5              
 [59] matrixStats_1.1.0           stats4_4.3.3               
 [61] spatstat.explore_3.5-2      jsonlite_2.0.0             
 [63] GetoptLong_1.0.5            ellipsis_0.3.2             
 [65] tidygraph_1.3.0             progressr_0.15.1           
 [67] iterators_1.0.14            ggridges_0.5.7             
 [69] ggalluvial_0.12.5           survival_3.8-3             
 [71] systemfonts_1.2.3           foreach_1.5.2              
 [73] tools_4.3.3                 ggnewscale_0.5.2           
 [75] ragg_1.5.0                  stringdist_0.9.15          
 [77] ica_1.0-3                   Rcpp_1.1.0                 
 [79] glue_1.8.0                  gridExtra_2.3              
 [81] SparseArray_1.2.2           qs2_0.1.5                  
 [83] qvalue_2.34.0               MatrixGenerics_1.14.0      
 [85] GenomeInfoDb_1.38.1         withr_3.0.2                
 [87] fastmap_1.2.0               fansi_1.0.6                
 [89] SparseM_1.84-2              digest_0.6.37              
 [91] R6_2.6.1                    mime_0.13                  
 [93] textshaping_0.4.0           colorspace_2.1-1           
 [95] Cairo_1.6-2                 scattermore_1.2            
 [97] tensor_1.5.1                dichromat_2.0-0.1          
 [99] spatstat.data_3.1-8         generics_0.1.4             
[101] data.table_1.17.8           graphlayouts_1.2.2         
[103] httr_1.4.7                  htmlwidgets_1.6.4          
[105] S4Arrays_1.2.0              uwot_0.2.3                 
[107] pkgconfig_2.0.3             gtable_0.3.6               
[109] ComplexHeatmap_2.18.0       lmtest_0.9-40              
[111] SingleCellExperiment_1.24.0 XVector_0.42.0             
[113] htmltools_0.5.8.1           fgsea_1.28.0               
[115] dotCall64_1.2               clue_0.3-66                
[117] scales_1.4.0                Biobase_2.62.0             
[119] png_0.1-8                   spatstat.univar_3.1-4      
[121] ggdendro_0.2.0              rjson_0.2.23               
[123] reshape2_1.4.4              nlme_3.1-168               
[125] cachem_1.1.0                zoo_1.8-14                 
[127] GlobalOptions_0.1.2         stringr_1.5.2              
[129] KernSmooth_2.23-26          parallel_4.3.3             
[131] miniUI_0.1.2                pillar_1.11.0              
[133] grid_4.3.3                  logger_0.4.0               
[135] vctrs_0.6.5                 RANN_2.6.2                 
[137] VGAM_1.1-13                 promises_1.3.3             
[139] stringfish_0.17.0           xtable_1.8-4               
[141] cluster_2.1.8.1             truncdist_1.0-2            
[143] cli_3.6.5                   compiler_4.3.3             
[145] crayon_1.5.3                future.apply_1.20.0        
[147] labeling_0.4.3              plyr_1.8.9                 
[149] forcats_1.0.0               stringi_1.8.7              
[151] BiocParallel_1.36.0         viridisLite_0.4.2          
[153] deldir_2.0-4                scplotter_0.6.2            
[155] assertthat_0.2.1            gsl_2.1-8                  
[157] lazyeval_0.2.2              spatstat.geom_3.5-0        
[159] quantreg_6.1                Matrix_1.6-5               
[161] RcppHNSW_0.6.0              patchwork_1.3.2            
[163] future_1.67.0               shiny_1.11.1               
[165] plotthis_0.8.2              SummarizedExperiment_1.32.0
[167] evd_2.3-7.1                 ROCR_1.0-11                
[169] gridtext_0.1.5              memoise_2.0.1              
[171] igraph_2.1.4                RcppParallel_5.1.9         
[173] bracer_1.2.1                fastmatch_1.1-6

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Command: stdbuf -oL Rscript /mnt/disks/.cwd/.pipen/Immunopipe/ScFGSEA/0/job.script
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Major page faults: 0
Minor page faults: 1558955
Maximum resident set size (kB): 4303180
Elapsed real time (s): 230.67
System (kernel) time (s): 2.39
User time (s): 226.15
Exit status: 0